- Implement an infrastructure for clinical genomic sequencing and interpretation.
- Build public trust in genomic medicine.
- Urge insurance companies to reimburse genome sequencing in clinical settings.
The Institute for Genomic Medicine is a division of the
Utah Foundation for Biomedical Research,
a 501(c)3 non-profit organization
Patients are not just anonymous “subjects” in our research studies. Instead, we talk to patients and their families directly, and we aim to return research results to them in a scientifically rigorous manner.
Leslie, a six-year old girl, has suffered from several episodes of severe seizures ever since she was born. Not knowing the exact cause of the seizures, she was treated with epilepsy drugs, which may have caused adverse reactions over time and delayed normal intellectual and physiological development. After consulting with experienced cytogeneticists, she was diagnosed with a previously unreported chromosomal imbalanced translocation, but the exact genetic cause of the seizures remains a mystery.
Leslie is one of the patients being helped by IGM. We have performed whole-genome sequencing of Leslie and are identifying the exact genes underpinning the seizures, and this information may help in guiding future treatment options.
We reach out to selected patients who may benefit from genome sequencing the most, given their clinical information and all prior knowledge on the diseases. Our doctors collect blood samples from the patients, and then work with CLIA-certified laboratories to obtain sequencing data. Our bioinformaticians analyze the data and generate tiered interpretation of the data. Our genetic counselors and data analysts then return the results to patients and physicians. At the same time, the patient can optionally participate in our IRB-approved research study, so that information from his/her genome can contribute to our understanding of human genetic variation and human diseases.
IGM pays to perform whole-genome sequencing on patients, analyze the sequence data and return the results to patients and their families. These costs are unfortunately typically not reimbursed by insurance companies. Our operation therefore relies completely on contributions from donors and the founders.
Currently, IGM is established under the auspices of Utah Foundation for Biomedical Research, a non-profit organization that is dedicated to improving lives through the advancement of science. We are a registered 501(c)3 organization. Your gift to IGM is tax deductible to the extent allowed by the law.
The Institute for Genomic Medicine (IGM) is a 501(c) 3 non-profit organization associated with the Utah Foundation for Biomedical Research, aiming to promote the implementation of Genomic Medicine.
The leadership of IGM consists of: Dr. Gholson Lyon, Dr. Reid Robison, Dr. Kai Wang, and Dr. Clark Johnson. There are currently a team of volunteers working to expand IGM.